ISO 5840 Steady-Flow Heart Valve Test Rig
Provides straight upstream and anatomical sinus of Valsalva downstream flow conduits with pressure taps.
Biomedical Engineering / Heart Valve Steady Pressure Drop
FREE TO EXPLORELABORATORY 30 · BIOMEDICAL ENGINEERING
Bileaflet Mechanical Heart Valve Steady-Flow Pressure Drop & Orifice Area
Measure the transvalvular pressure gradient ΔP across a 25 mm bileaflet mechanical aortic heart valve under steady forward flow and evaluate the quadratic Bernoulli loss coefficient k_v. Explore interactive physiological instrumentation simulation, biomechanics, and biomedical engineering telemetry.
BIOINSTRUMENTATION · BIOSIGNALS · BIOMECHANICS · IMAGING
Your virtual biomedical engineering laboratory.
TRANSVALVULAR PRESSURE DROP ΔP—
PHYSIOLOGICAL & TEST CELL TELEMETRY
Ready to sample with Velocity v = 1.4 m/s.
Adjust Velocity v, then execute biomedical trial.
Biomedical engineering telemetry and physiological states are evaluated rigorously using 64-bit IEEE 754 precision. Residuals reflect ordinary least-squares regression across successive observations. Continuous data structures support high-fidelity biological and physiological modeling.
Biomedical assumptions and boundary condition limits
Steady forward flow does not simulate transient valve opening/closing leaflet dynamics or dynamic regurgitation phases. Evaluated on a 25 mm bileaflet pyrolytic carbon mechanical aortic valve mounted in an acrylic aortic root chamber meeting ISO 5840 standards. Perfusion fluid is 36% glycerol blood analog (density ρ = 1055 kg/m³, viscosity 3.6 cP at 37 °C). Velocities v = 1.0, 1.2, 1.4, 1.6, 1.8, 2.0 m/s correspond to v² = 1.00, 1.44, 1.96, 2.56, 3.24, 4.00 m²/s². Quadratic Bernoulli slope k_v = 3.8500 mmHg/(m²/s²).
Biomedical apparatus & physiological sensors.
25 mm Pyrolytic Carbon Bileaflet Mechanical Aortic Valve
Clinical prosthesis with dual semicircular pyrolytic carbon leaflets and Dacron sewing cuff.
Variable-Speed Centrifugal Perfusion Pump
Supplies stable, continuous non-pulsatile forward flow from 5 to 35 L/min.
Differential Wet-Wet Differential Pressure Transducer
Measures transvalvular pressure drop ΔP with pressure taps located 1 diameter upstream and 3 diameters downstream.
Ultrasonic Clamp-On Flowmeter (Transonic Systems)
Measures volumetric forward flow rate Q with 1% accuracy and sub-millisecond response.
Thermostatically Controlled Glycerol-Water Reservoir (37.0 °C)
Maintains fluid density ρ = 1055 kg/m³ and blood-analog viscosity 3.6 cP.
FOLLOW THE METHOD
A reason behind every step.
Measure the transvalvular pressure gradient ΔP across a 25 mm bileaflet mechanical aortic heart valve under steady forward flow and evaluate the quadratic Bernoulli loss coefficient k_v. Standardized parameter settings: 1.0, 1.2, 1.4, 1.6, 1.8, 2.0 m/s.
01
Valve Mounting and Alignment Verification
Mount 25 mm mechanical valve securely in acrylic test chamber, ensuring leaflets open symmetrically without sewing ring impingement.
02
Perfusion Fluid Priming and Temperature Stabilization
Fill system with 36% glycerol-water blood analog, purge all trapped air from pressure lines, and heat reservoir to 37.0 °C.
03
Zero Differential Pressure Baseline
Open transducer bypass valve at zero flow to establish precise 0.00 mmHg baseline differential pressure.
04
Velocity Increment and Stabilization
Adjust centrifugal pump to establish transvalvular jet velocity v = 1.0 m/s (verified by flowmeter Q and effective orifice area) and record steady pressure drop ΔP.
05
Velocity Progression Sequence
Increment jet velocity through 1.2, 1.4, 1.6, 1.8, and 2.0 m/s, recording stabilized pressure gradient ΔP over 30 seconds at each step.
06
Bernoulli Quadratic Regression Analysis
Plot transvalvular pressure drop ΔP against v², compute the slope k_v via linear regression through the origin, and calculate effective orifice area EOA.
YOUR NOTEBOOK · 0 OBSERVATIONS
Turn measurements into biomedical engineering insight.
Points are your recorded observations. The solid regression line validates Heart Valve Steady Pressure Drop mathematical scaling.
LINEAR REGRESSION FIT · y = mx + b
ΔP = k_v · v² = 3.8500 · v²
| # | Transvalvular Jet Velocity v (m/s) | Transvalvular Pressure Drop ΔP (mmHg) | Square of transvalvular velocity v² (m²/s²) | Transvalvular pressure drop ΔP (mmHg) | Remove |
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